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Neurology Xagena

Roche has announced positive results from two pivotal studies evaluating the investigational medicine Ocrelizumab compared with Interferon beta-1a ( Rebif ), a standard-of-care therapy, in people with ...


The first non-vitamin K antagonist oral anticoagulant ( NOAC ) introduced to the market in Japan was Dabigatran ( Pradaxa ) in March 2011, and three more NOACs, Rivaroxaban ( Xarelto ), Apixaban ( Eli ...


Although multiple sclerosis is thought to represent an excessive and inappropriate immune response to several central nervous system ( CNS ) autoantigens, increasing evidence also suggests that multip ...


Multiple sclerosis is triggered by self-reactive T cells that successfully infiltrate the brain and spinal cord where they launch an aggressive autoimmune attack against myelin. Over time, the resulti ...


Modern scientific understanding has considered multiple sclerosis to be a disease controlled by the T cell, a type of white blood cell. Research has shown that in multiple sclerosis, T cells inappropr ...


The phase 3 ASCEND study investigating Natalizumab ( Tysabri ) in the treatment of secondary progressive multiple sclerosis ( SPMS ) did not achieve its primary and secondary endpoints. During the stu ...


The purpose was to report the effects of delayed-release Dimethyl fumarate ( DMF; also known as gastro-resistant DMF ) on the number of relapses requiring intravenous ( IV ) steroids and multiple scle ...


Uric acid may lessen women’s disability after stroke, according to new research published in Stroke, journal of American Heart Association ( AHA ). High levels of Uric acid can lead to kidney ston ...


Researchers have analyzed the evolution of non-motor symptoms and patients’ and neurologists’ clinical global impression ( CGI ) in advanced Parkinson's disease patients treated with Levodopa–Carbidop ...


Extensive published evidence supports the use of subcutaneously-administered Apomorphine as an effective therapy for Parkinson's disease ( PD ) but to date no consensus recommendations have been avail ...


A study has compared the effectiveness ( percentage of change in daily ON, OFF and dyskinesia times ) and tolerability of Levodopa-Carbidopa intestinal gel ( LCIG; Duodopa; Duopa ) in patients with Pa ...


The aim of a study was to compare the safety and efficacy of Botulinum toxin type-A ( BTX-A ) versus anticholinergic therapy as Biperiden HCl in the treatment of cervical dystonia patients. After f ...


Pooling of efficacy data across studies can provide a more precise estimate of overall treatment effect, treatment effect for endpoints measured infrequently, and variation of effect across subgroups ...


Researchers have evaluated the efficacy and the safety of a prolonged release oral formulation of Oxycodone hydrochloride combined with Naloxone hydrochloride dehydrate, in a fixed ratio of 2:1 ( OXN ...


A study has compared baseline characteristics between patients with advanced Parkinson's disease who continued with Levodopa-Carbidopa intestinal gel [ LCIG; Duodopa; Duopa ] ( contLCIG ) and patients ...