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Neurology Xagena

A study has compared the effectiveness ( percentage of change in daily ON, OFF and dyskinesia times ) and tolerability of Levodopa-Carbidopa intestinal gel ( LCIG; Duodopa; Duopa ) in patients with Pa ...


The aim of a study was to compare the safety and efficacy of Botulinum toxin type-A ( BTX-A ) versus anticholinergic therapy as Biperiden HCl in the treatment of cervical dystonia patients. After f ...


Pooling of efficacy data across studies can provide a more precise estimate of overall treatment effect, treatment effect for endpoints measured infrequently, and variation of effect across subgroups ...


Researchers have evaluated the efficacy and the safety of a prolonged release oral formulation of Oxycodone hydrochloride combined with Naloxone hydrochloride dehydrate, in a fixed ratio of 2:1 ( OXN ...


A study has compared baseline characteristics between patients with advanced Parkinson's disease who continued with Levodopa-Carbidopa intestinal gel [ LCIG; Duodopa; Duopa ] ( contLCIG ) and patients ...


Levodopa-Carbidopa intestinal gel ( LCIG ) was evaluated for the treatment of dyskinesia in a subgroup of advanced Parkinson’s disease ( PD ) patients with relevant dyskinesia. Oral Levodopa therap ...


Biotin, used at high dose, has some impact on disease progression and permanent disability in patients with progressive multiple sclerosis. Overall, 21/23 patients ( 91.3% ) exhibited some qualitative ...


No drug has been found to have any impact on progressive multiple sclerosis ( MS ). Biotin is a vitamin acting as a coenzyme for carboxylases involved in key steps of energy metabolism and fatty acids ...


In a study published in The Journal of Experimental Medicine, researchers, at the Wihuri Research Institute and the University of Helsinki, have reported a surprising finding that challenges current a ...


Cardiovascular disease is a recognized contributor to the pathogenesis of Alzheimer's disease. Heart failure is a cardiovascular subtype that can be used to model the contribution of cardiovascular di ...


Positive results from the pivotal phase III clinical trial, MS-SPI were presented at the American Academy of Neurology Annual Meeting. The study demonstrated evidence of the efficacy and safety of M ...


Cysteine could potentially lower the risk of stroke through antihypertensive and antioxidant effects. A study has evaluated the hypothesis that cysteine intake is inversely associated with stroke in ...


Twenty-three patients aged from 26 to 75 years ( mean=52.8 years ) were treated with high doses of Biotin from 2 to 36 months ( mean treatment׳s duration=9.2 months ). Fourteen patients suffered fro ...


A research presented at the International Stroke Conference ( ISC ) and published in The New England Journal of Medicine ( NEJM ) found that the addition of the Solitaire Device stent thrombectomy pro ...


Data from a pre-specified interim analysis of PRIME, the phase 1b study of Aducanumab ( BIIB037 ) were presented at the 12th International Conference on Alzheimer's and Parkinson's Diseases and Relate ...