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Levodopa-Carbidopa intestinal gel ( LCIG ) was evaluated for the treatment of dyskinesia in a subgroup of advanced Parkinson’s disease ( PD ) patients with relevant dyskinesia. Oral Levodopa therap ...


Biotin, used at high dose, has some impact on disease progression and permanent disability in patients with progressive multiple sclerosis. Overall, 21/23 patients ( 91.3% ) exhibited some qualitative ...


No drug has been found to have any impact on progressive multiple sclerosis ( MS ). Biotin is a vitamin acting as a coenzyme for carboxylases involved in key steps of energy metabolism and fatty acids ...


In a study published in The Journal of Experimental Medicine, researchers, at the Wihuri Research Institute and the University of Helsinki, have reported a surprising finding that challenges current a ...


Cardiovascular disease is a recognized contributor to the pathogenesis of Alzheimer's disease. Heart failure is a cardiovascular subtype that can be used to model the contribution of cardiovascular di ...


Positive results from the pivotal phase III clinical trial, MS-SPI were presented at the American Academy of Neurology Annual Meeting. The study demonstrated evidence of the efficacy and safety of M ...


Cysteine could potentially lower the risk of stroke through antihypertensive and antioxidant effects. A study has evaluated the hypothesis that cysteine intake is inversely associated with stroke in ...


Twenty-three patients aged from 26 to 75 years ( mean=52.8 years ) were treated with high doses of Biotin from 2 to 36 months ( mean treatment׳s duration=9.2 months ). Fourteen patients suffered fro ...


A research presented at the International Stroke Conference ( ISC ) and published in The New England Journal of Medicine ( NEJM ) found that the addition of the Solitaire Device stent thrombectomy pro ...


Data from a pre-specified interim analysis of PRIME, the phase 1b study of Aducanumab ( BIIB037 ) were presented at the 12th International Conference on Alzheimer's and Parkinson's Diseases and Relate ...


Increasing evidences link T helper 17 ( Th17 ) cells with multiple sclerosis ( MS ). In this context, interleukin-22 ( IL-22 ), a Th17-linked cytokine, has been implicated in blood brain barrier break ...


In 85% of cases, multiple sclerosis ( MS ) initially evolves through relapses that resolve completely or incompletely ( relapsing-remitting multiple sclerosis or RRMS ). However, in about 50% of cas ...


Teva Pharmaceutical has announced the successful completion of its Phase IIb migraine prevention program with positive top-line results from a Phase IIb study evaluating the efficacy, safety and toler ...


Hemicrania continua is a strictly unilateral, continuous headache, typically mild to moderate in severity, with severe exacerbations commonly accompanied by cranial autonomic features and migrainous s ...


The purpose of a study was to monitor weight regain after therapy discontinuation in patients with migraine experiencing weight loss during Topiramate ( Topamax ) treatment. Patients with migraine ...